Why does my combination of 1000mg Depakote, 150mg Venlafaxine and 2mg Risperidone make me put on weight

Weight gain is one of the side effect of Risperidone, with one study finding that 26 to 38 percent of participants on the drug experienced weight gain. Of the people who gain weight, most is gain during the first 6 to 12 months of treatment. It then tends to level out. If u do start to put on weight or have problems with ur weight, u should tell ur doctor. He or she may be able to adjust ur drug or the dose of ur drug to reduce this effect. All the other drugs u mentioned r associated with decreased appetite so probably, it is just the Risperidone that makes u put on weight.

I am assuming this is for bipolar disorder. I am also bipolar & have used plenty of meds.
I do not mind the weight gain since I am a powerlifter so it is a massive benefit to me.

I do know what u mean though.
Many meds do this. Anti-psychotics r especially bad for weight gain.

Why they do it is a little more tricky. Some of them increase ur appetite. Some of them affect the message to ur brain that you're full. Basically whatever they do they make u hungry. Some of them also affect ur metabolism. It also does not affect everyone the same.

It is pretty tricky to deal with. Because they affect ur brain chemistry, exercise & diet often makes little difference. Although eating healthily & exercising does help to an extent & it will minimise ur symptoms.
You also do not want to stop the meds because the lack of meds will make ur life hell. Another problem is that gaining weight does not exactly help the episodes of depression.

The only thing that really works is speaking to ur doctor. Tell them you're gaining & they will most likely help u find medications that wo not or will do so to a lesser extent. I am sure u understand that it is a trial & error process so prepare for a long process.

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